제 257회 NEBS Monthly meeting 개최를 다음과 같이 알려드립니다.
일시: 2017년 8월 31일 (목요일) 오후 6시 30분
(7시 이후 엘레베이터 이용이 제한되니 가급적 7시 이전에 오시길 부탁드리며, 7시 이후의 경우 Security guard에게 미팅 참석 여부를 확인 후 엘리베이터 이용을 부탁해 주세요.)
New Research Building, 10th floor conference room
77 Ave Louis Pasteur, Boston, MA 02115
6:20 - 7:00 저녁식사
7:00 - 7:10 공지사항
7:10 – 7:55 Presentation 1 -
“Feature extraction and dimensionality reduction of breast cancer cell data using memristor networks"
By Shinhyun Choi, Ph.D. (MIT)
7:55 - 8:40 Presentation 2 –
“Gut-brain axis in C. Elegans”
By Kiho Lee, Ph.D. (Brown University)
9:00 - 11:00 뒷풀이 (Longwood Grill)
발표 관련 abstract는 아래를 참조 바랍니다.
Feature Extraction and Dimensionality Reduction of Breast Cancer Cell Data Using Memristor Networks
Memristors have been considered as a leading candidate for a number of critical applications ranging from nonvolatile memory to non-Von Neumann computing systems. Feature extraction, which aims to transform input data from a high-dimensional space to a space with fewer dimensions, is an important technique widely used in machine learning and pattern recognition applications. Here, we experimentally demonstrate that memristor arrays can be used to perform principal component analysis, one of the most commonly used feature extraction techniques, through online, unsupervised learning. Using Sanger’s rule, that is, the generalized Hebbian algorithm, the principal components were obtained as the memristor conductances in the network after training. The network was then used to analyze sensory data from a standard breast cancer screening database with high classification success rate (97.1%).
Gut-brain axis in C. elegans
Changes in gut microbiota affect memory and behavior. The free-living soil nematode Caenorhabditis elegans uses bacteria as a food source and discriminates pathogens from beneficial bacteria. The intestine of the nematode plays a critical role in recognizing stress and prompting avoidance behavior. However, the molecules that relay the recognized stress have not been identified previously. Aim of this study is to evaluate the hypothesis: What molecules from the intestine can influence neuronal cells and actively modify avoidance behavior. We found that an intestine-secreted insulin-like neuropeptide negatively controls signal pathways in neurons that promote avoidance behavior. Transcriptional regulations that depended on the available food source and affected the survival rate and egg-laying rate. Overall, remembrance of noxious environment has to be balanced and feedback mechanism might allow this model host to actively balance in changing environments.